论文部分内容阅读
目的:回顾分析我院下呼吸道感染的病原菌分布和药物敏感情况,为临床合理应用抗菌药物提供依据。方法:对2012-2014年我院呼吸内科下呼吸道感染住院患者的痰菌培养及药敏结果进行分析。结果:1564例患者培养出378株病原菌,阳性率为24.1%。其中双重感染165例。其中革兰阴性菌191株,所占比例为50.5%,主要是克雷伯菌属、铜绿假单胞菌和鲍氏不动杆菌。革兰阳性球菌98株,主要为金黄色葡萄球菌和表皮葡萄球菌。真菌89株,主要为白色假丝酵母菌。革兰氏阴性菌对哌拉西林、头孢哌酮和头孢他啶的敏感性较高。金黄色葡萄球菌对庆大霉素、环丙沙星和头孢他啶的敏感性较低,小于50%。结论:呼吸内科患者下呼吸道感染以革兰阴性杆菌感染为主。临床上应加强对药物的管理和合理应用抗菌药物以减少病原菌耐药性的产生。
Objective: To retrospectively analyze the distribution of pathogenic bacteria and drug sensitivity in lower respiratory tract infection in our hospital, and to provide the basis for rational use of antibacterials in clinic. Methods: The sputum culture and drug susceptibility results of hospitalized patients with respiratory tract infection from 2012 to 2014 in our hospital were analyzed. Results: A total of 378 strains of pathogens were cultured in 1564 patients, the positive rate was 24.1%. One double infection in 165 cases. Among them, 191 were Gram-negative bacteria, accounting for 50.5%, mainly Klebsiella, Pseudomonas aeruginosa and Acinetobacter baumannii. Gram-positive cocci 98, mainly Staphylococcus aureus and Staphylococcus epidermidis. 89 fungi, mainly Candida albicans. Gram-negative bacteria were more susceptible to piperacillin, cefoperazone and ceftazidime. Staphylococcus aureus to gentamicin, ciprofloxacin and ceftazidime sensitivity is low, less than 50%. Conclusions: Gram-negative bacilli infection is the main cause of lower respiratory tract infection in respiratory patients. Clinically, we should strengthen the management of drugs and rational use of antimicrobial agents to reduce the generation of pathogenic bacteria drug resistance.