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目的:探讨钼靶X线摄影、MRI动态增强(DCE-MRI)及弥散加权成像(DWI)联合检查对乳腺癌的诊断价值。方法:选择2013年1月至2015年10月南京市高淳人民医院门诊或影像学检查发现乳腺病变者105例为研究对象,分别以钼靶X线摄影、DCE-MRI及DWI进行检查,所有病灶均以手术或穿刺活检确诊病理结果。结果:128个病灶中恶性病灶87个(69例),均为乳腺癌,其年龄、短径均显著大于良性病变者(P<0.05)。钼靶X线成功显示出67个乳腺癌病灶,DCE-MRI成功显示出78个乳腺癌病灶,DWI成功显示出84个乳腺癌病灶。三者联合诊断的准确性、敏感性及特异性分别为97.7%、98.8%、95.1%,均显著高于单独诊断(P<0.05)。结论:钼靶X线摄影、DCE-MRI及DWI 3种影像学手段各有适用范围,三者联合可显著提高乳腺癌诊断的准确性、敏感性和特异性。
Objective: To investigate the diagnostic value of mammography, DCE-MRI and diffusion-weighted imaging (DWI) in the diagnosis of breast cancer. Methods: From January 2013 to October 2015, 105 cases of breast lesions in outpatient department or imaging examination of Gaochun People’s Hospital in Nanjing were selected as research objects, which were examined by mammography, DCE-MRI and DWI respectively. All lesions Pathological findings were confirmed by surgery or biopsy. Results: There were 87 malignant lesions (n = 69) in 128 lesions, all of which were breast cancer. Their age and short diameter were significantly larger than those of benign lesions (P <0.05). Molybdenum target X-ray successfully demonstrated 67 breast lesions, DCE-MRI successfully demonstrated 78 breast lesions, and DWI successfully demonstrated 84 breast lesions. The accuracy, sensitivity and specificity of the combined diagnosis of the three were 97.7%, 98.8% and 95.1%, respectively, which were significantly higher than those of single diagnosis (P <0.05). Conclusion: Three mammography, DCE-MRI and DWI imaging methods have their own scope of application, the combination of the three can significantly improve the accuracy of breast cancer diagnosis, sensitivity and specificity.