患者女性,30岁,于1965年8月21日突然畏塞、颤抖,高热达41℃,伴剧烈头痛及全身关节痛,4～5小时后出汗热退。这样的寒热症状连续4天后,发热持续不退,高热时神昏谵语,并呕吐二次,曾服中药二付无效,乃于8月28日转入我院。平秦身体健康,既往无瘧疾发作史。入院时体温40.2℃,血涂片检出恶性瘧原虫(环状体)。当即以硫酸奎宁及伯氨喹口服,因服药后恶心、呕吐较剧,乃于次日改用二盐酸奎宁(上海第一制药厂出品)肌注,每日0.75克分三次给予,连续7天总量达5.25克,仍高热弛张,并于住院第7～9天 A 30-year-old female patient suddenly feared and trembled on August 21, 1965 with a fever of 41 ° C. She had severe headache and generalized joint pain and sweating fever after 4 to 5 hours. This cold and heat symptoms for 4 days in a row, fever continued unabated, high fever when fainting, and vomiting twice, served twice to pay Chinese medicine invalid, was transferred to our hospital on August 28. Ping Qin good health, past history of malaria episodes. On admission, the body temperature was 40.2 ° C, and blood smears detected P. falciparum (annulus). Immediately with quinine sulfate and primaquine orally, due to medication nausea, vomiting more drama, but the next day to switch to quinine dihydrochloride (Shanghai First Pharmaceutical Factory produced intramuscular injection of 0.75 g daily for three times in a row, continuous 7 days total amount of 5.25 grams, still hot relaxation, and in the hospital from 7 to 9 days