神经纤维瘤病可恶变为恶性神经鞘癌,但合并恶性黑色素瘤(下称恶黑)尚未见报告,现报告一例于下.男性,52岁,先天性背部色素斑,随年龄增长逐渐扩展波及整个背部.十余年前右下背出现囊性肿物,缓慢增大但病变皮肤除不出汗外无其它不适.1981年3月偶然发现右肩胛下有蚕豆大小皮下结节.肿块切除后病理检查报告为“淋巴结转移性恶黑”(见图1). Neurofibromatosis has become a malignant nerve sheath cancer, but malignant melanoma (hereinafter referred to as evil black) has not yet been reported. One case is reported below. Male, 52 years old, with congenital dorsal pigment spots, gradually spread with age The entire back. A cystic mass appeared in the right lower back more than 10 years ago, but slowly increased but the skin was not discomfortable except in sweating. In March 1981, a subcutaneous nodule with the size of faba bean was accidentally found in the right shoulder and below the mass. The pathological examination was reported as “metastasis of lymph node metastasis” (see Figure 1).