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目的:探讨1.22%甲硝唑氯化钠坐浴液联合化痔栓对急性白血病患者化疗后肛周感染临床疗效。方法:将120例急性白血病化疗患者随机分为自制1.22%甲硝唑氯化钠坐浴液组、1.22%甲硝唑氯化钠坐浴液联合化痔栓组及对照组各40例,分别采用1.22%甲硝唑氯化钠坐浴、1.22%甲硝唑氯化钠坐浴液坐浴后给予化痔栓治疗、1∶5 000高锰酸钾坐浴方法,比较3组患者在治疗14 d后肛周感染的治愈率、肛周皮肤黏膜红肿情况、疼痛程度、排便情况、肛周培养结果。结果:3组患者治疗效果比较,差异有统计学意义(P<0.05)。结论:1.22%甲硝唑氯化钠坐浴液联合化痔栓治疗急性白血病患者化疗后肛周感染疗效优于传统的1∶5 000高锰酸钾坐浴治疗,是一种行之有效的治疗方法,值得临床上推广使用。
Objective: To investigate the clinical efficacy of 1.22% metronidazole sodium chloride bath combined with Shuganzhe suppository in patients with acute leukemia after perianal infection. Methods: One hundred and twenty patients with acute leukemia were randomly divided into self-made metronidazole sodium chloride bath group (1.22%), metronidazole sodium chloride combined with hydrocephalus group (40 cases) and control group (40 cases) Using 1.22% metronidazole sodium chloride bath, 1.22% metronidazole sodium chloride bath after bath to give the hemorrhoid suppository treatment, 1: 5000 potassium permanganate bath method, the three groups of patients in the treatment After 14 days, the cure rate of perianal infection, perianal skin mucosal swelling, pain, defecation, perianal culture results. Results: The treatment effect of the three groups was statistically significant (P <0.05). Conclusion: 1.22% metronidazole sodium chloride bath combined with Shuzheng suppository in the treatment of acute leukemia in patients with perianal infection after chemotherapy than traditional 1: 5000 potassium permanganate bath treatment is an effective Treatment, it is worth promoting the clinical use.