碘海醇——新型非离子型碘水造影剂

来源 :新药与临床 | 被引量 : 0次 | 上传用户:jenjen1985
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
碘海醇(iohexol,Omnipaque)是一种新型的非离子型碘水造影利;显影质量可靠,可广泛使用于脑室造影、全脊髓蛛网膜下腔造影、增强的CT扫描以及进行包括数字减影动脉造影在内的各种血管造影。其毒性与副作用均较甲泛葡胺(metriza-midc,Amipaquc)更小;自1983年临床应用后尚无发生惊厥的报道。常用剂型为溶液,性状稳定,使用方便。作者应用于临床47例次造影检查,取得满意效果,无严重副作用,故认为碘海醇是目前理想的、多种用途的造影剂。 Iohexol (Omnipaque) is a new non-ionic iodine-water contrast medium with reliable development and is widely used in ventriculography, whole-spinal subarachnoid angiography, enhanced CT scans, and digital subtraction Angiography, including angiography. Its toxicity and side effects are smaller than metrizine (metriza-midc, Amipaquc); since 1983, no clinical reports of convulsions. Commonly used as a solution, stable performance, easy to use. The authors applied 47 cases of clinical angiography, and achieved satisfactory results, no serious side effects, it is believed that iohexol is the ideal, multi-purpose contrast agent.
其他文献
1-(β-苯乙基)-4-哌啶酮(1)是制备芬太尼等多种强效麻醉镇的药的重要中间体。其合成路线为: 1- (β-Phenethyl) -4-piperidone (1) is an important intermediate for the