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目的:观察解毒化瘀颗粒联合西药治疗慢性乙型肝炎重症化倾向期的临床疗效。方法:将112例慢性乙型肝炎重症化倾向期患者随机分为两组各56例,对照组采用西医综合治疗,治疗组在对照组治疗的基础上加用解毒化瘀颗粒口服治疗,观察两组患者治疗前后证候积分、肝功能、凝血功能、肝衰竭转化及整体疗效情况。结果:总有效率治疗组为92.86%,对照组为78.57%,两组比较,差异有统计学意义(P<0.05);且治疗组患者治疗后证候积分、肝功能、凝血功能、肝衰竭转化情况均优于对照组(P<0.05)。结论:以解毒化瘀颗粒为主的中西医结合治疗方案治疗慢性乙型肝炎重症化倾向期疗效优于单纯西医治疗。
Objective: To observe the clinical effects of Jiedu Huayu granules combined with western medicine on the treatment of chronic severe hepatitis. Methods: One hundred and twenty-two chronic hepatitis B patients with severe intestine tended to be randomly divided into two groups of 56 cases each. The control group was treated with western medicine. The treatment group was treated with detoxification and blood stasis granules on the basis of the control group. Before and after treatment in patients with syndrome points, liver function, coagulation, liver failure and the overall effect of conversion. Results: The total effective rate was 92.86% in the treatment group and 78.57% in the control group. There was significant difference between the two groups (P <0.05); and after treatment, the syndrome score, liver function, coagulation function, liver failure Conversion was better than the control group (P <0.05). Conclusion: The treatment of Integrative Medicine with traditional Chinese and western medicine based on Detoxification and Removing Stasis Granules is superior to western medicine in the treatment of chronic severe hepatitis.