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目的探讨利巴韦林联合高渗盐水治疗小儿毛细支气管炎的疗效观察及其对肺功能的影响分析。方法选择我院自2014年1月~2016年1月收治的100例毛细支气管炎患儿,随机分成对照组与观察组,各50例,对照组采用利巴韦林治疗,观察组在此基础上联合高渗盐水治疗,观察两组患者临床疗效、不良反应发生率及咳嗽、喘息、肺部哮鸣音、肺部湿啰音等肺部功能指证的变化情况。结果观察组总有效率显著高于对照组(P<0.05);观察组咳嗽、喘息、肺部哮鸣音、肺部湿啰音等消失时间及住院时间均显著低于对照组(P<0.05);两组不良反应发生率无明显差异(P>0.05)。结论利巴韦林联合高渗盐水治疗小儿毛细支气管炎能够显著改善患儿临床症状,缩短住院时间,改善肺功能,促进患者康复。
Objective To investigate the curative effect of ribavirin combined with hypertonic saline on pediatric bronchiolitis and its influence on pulmonary function. Methods A total of 100 children with bronchiolitis admitted to our hospital from January 2014 to January 2016 were randomly divided into control group and observation group, 50 cases each. The control group was treated with ribavirin. The observation group was on the basis of this On the combination of hypertonic saline treatment, clinical efficacy, incidence of adverse reactions and changes in lung function indicators such as cough, wheezing, lung wheeze and lung wet aura were observed. Results The total effective rate in the observation group was significantly higher than that in the control group (P <0.05). The disappearance time and hospitalization time of the cough, wheezing, pulmonary wheeze and lung wet rales in the observation group were significantly lower than those in the control group (P <0.05 ); There was no significant difference in the incidence of adverse reactions between the two groups (P> 0.05). Conclusion Ribavirin combined with hypertonic saline treatment of children with bronchiolitis can significantly improve the clinical symptoms of children, shorten the hospital stay, improve lung function and promote patient rehabilitation.