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目的通过超声测量Ⅱ型糖尿病(T2DM)患者的下肢动脉各项血流动力学参数,研究病程长短对糖尿病下肢动脉病变影响,寻求客观反映下肢动脉病变水平的超声观测新指标。方法对52例Ⅱ型糖尿病患者(共104条下肢动脉)行下肢动脉超声标准化测量,将所有受检对象按病程不同分为两组:糖尿病史≤15年者为1组,糖尿病史>15年者为2组,记录相关测量指标,包括髂外、股、腘、足背动脉收缩期峰值流速(PSV)、平均血流速度(TAMV)、血流量(BFV)和踝肱指数(ABI),计算PSV、TAMV和BFV的踝髂、踝股、踝腘指数,两组间各指标作独立样本t检验。结果 1组股动脉内径、足背动脉PSV、踝髂PSV指数、踝腘(PSV、TAMV、BFV)指数的均值大于2组,组间比较具有统计学意义(P<0.05);1组股动脉(PSV、TAMV)和腘动脉(PSV、TAMV)的均值小于2组,组间比较具有统计学意义(P<0.05)。结论对比以往指标,踝髂、踝股、踝腘等指数可客观、分节段反映Ⅱ型糖尿病患者下肢动脉病变程度。
Objective To measure the hemodynamic parameters of lower extremity arteries in patients with type 2 diabetes mellitus (T2DM) by ultrasound and to study the influence of duration of diabetes on the arterial disease of lower extremities in patients with diabetes mellitus. Methods Fifty-two patients with type 2 diabetes mellitus (104 lower extremity arteries) underwent standardized arterial ultrasonography. All subjects were divided into two groups according to their duration of disease: one group with diabetes history ≤ 15 years and a history of diabetes> 15 years The patients were divided into two groups and recorded relevant measurement indexes including PSI, BFAM and ABI in the external ilium, the femoral head, the uterus, the dorsalis pedis artery, the mean systolic peak flow velocity (PSV), the mean flow velocity (TAMV) The ankle, malleolus and ankle index of PSV, TAMV and BFV were calculated, and each index was used as independent sample t-test. Results The mean values of PSV, PSV, PSV, TAMV and BFV index of femoral artery in 1 group were significantly higher than those in 2 groups (P <0.05). The femoral artery in group 1 (PSV, TAMV) and popliteal artery (PSV, TAMV) were less than 2 groups, with statistical significance (P <0.05). Conclusion Compared with previous indexes, the indices such as ankle, iliac, ankle and ankle can reflect the degree of lower extremity arterial disease in patients with type Ⅱ diabetes objectively and segmented.