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干细胞(stem cell)是一类具有自我更新能力和多向分化增殖潜能的原始细胞,包括胚胎干细胞(embryonic stem cell,ES)、成体干细胞(adult stemcell)。研究发现肿瘤细胞与干细胞都具有无限增殖和分化潜能的特点,而且还存在相似的调节自我更新的信号通路[1]。人们提出了肿瘤干细胞(
Stem cells are a group of primitive cells with self-renewal ability and multipotential differentiation and proliferation potential, including embryonic stem cells (ES) and adult stem cells. Studies have found that both tumor cells and stem cells have the potential to proliferate and differentiate indefinitely, and there are similar signaling pathways that regulate self-renewal [1]. People have proposed cancer stem cells (