我们于１９９７年６月遇到２例按常规浓度及用量地卡因溶液行表面麻醉时出现严重变态反应的患者，现报告如下。１病例报告例１，男，６４岁，于１９９７年１２月４日来本科就诊。主诉：有进行性嘶哑、咳嗽和咽部不适感。诊断为右侧声带肿物，在间接喉镜下取活检。因咽喉部喷１ We met in June 1997 in 2 cases of conventional concentration and dosage of caffeine solution surface anesthesia in patients with severe allergic reaction, are as follows. Case report 1, male, 64 years old, came to the undergraduate department on December 4, 1997. Chief Complaint: Progressive hoarseness, cough and throat discomfort. Diagnosis of the right vocal cord tumor, under direct laryngoscopy biopsy. Spray throat 1