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目的观察盐酸米诺环素软膏治疗急性局限型智齿冠周炎的临床疗效。方法选择急性局限型智齿冠周炎269例,随机分为观察组135例和对照组134例;2组均进行常规盲袋冲洗之后,观察组一次性在盲袋注入适量盐酸米诺环素软膏;对照组则导入2%碘甘油,连续治疗4 d;2组均在治疗后的第5 d复诊,观察评价疗效,并进行统计学分析。结果观察组:显效98例(72.59%),有效28例(20.74%),无效9例(6.67%),总有效率93.33%。对照组:显效57例(42.54%),有效39例(29.10%),无效38例(28.36%),总有效率71.64%。观察组疗效优于对照组(P<0.05)。结论在智齿冠周炎治疗中,采用盐酸米诺环素软膏注入盲袋治疗急性局限型智齿冠周炎,减少了患者的复诊次数,且安全、有效,疗程短,值得基层推广使用。
Objective To observe the clinical effect of minocycline hydrochloride ointment in the treatment of acute confined wisdom teeth with pericoronitis. Methods A total of 269 cases of acute confined wisdom pericoronitis were randomly divided into observation group (135 cases) and control group (134 cases). After blind flushing in both groups, the observation group received one-time injection of minocycline hydrochloride ointment ; Control group was introduced 2% iodine glycerol, continuous treatment of 4 d; 2 groups were in the treatment of the 5th d referral, observation and evaluation of efficacy, and statistical analysis. Results In observation group, 98 cases (72.59%) were markedly effective, 28 cases (20.74%) were effective, 9 cases (6.67%) were ineffective, and the total effective rate was 93.33%. In the control group, 57 cases (42.54%) were markedly effective, 39 (29.10%) were effective, 38 (28.36%) were ineffective and the total effective rate was 71.64%. The observation group was better than the control group (P <0.05). Conclusions In the treatment of Wistar pericoronitis, the treatment of acute confined wisdom teeth with periapical periodontitis by minocycline hydrochloride ointment can reduce the frequency of referral, and is safe, effective and short course of treatment. It is worth to promote the use of minocyclus.