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临床资料患者,女,61岁,因“间断活动后呼吸困难3年、再发加重1周”入院。患者3年来反复发作劳力性呼吸困难和夜间阵发性呼吸困难,伴活动耐量下降,规律应用血管紧张素转化酶抑制剂(Angiotensin Converting Enzyme Inhibitor,ACEI)、β受体阻滞剂、利尿剂和洋地黄以及胸腔穿刺引流,可短期好转。既往有高血压、糖尿病史,控制良好;4年前行左侧乳腺癌切除术,术后病理示导管原位癌、局灶少量浸润,术前术后予TA方案(紫杉醇270mg,表柔比星110mg)化疗各4次(1次/3周),无复
Clinical data Patient, female, 61 years old, admitted to hospital due to dyspnoea after intermittent activity for 3 years and exacerbated by 1 week. Patients with recurrent exertional dyspnea and paroxysmal nocturnal dyspnea over the past three years, with decreased activity tolerance, regular application of angiotensin converting enzyme inhibitors (ACEI), beta blockers, diuretics and foreign Rehmannia and thoracentesis can be short-term improvement. Previous history of hypertension and diabetes mellitus was well controlled. Left breast cancer resection was performed 4 years ago. Postoperative pathology showed ductal carcinoma in situ with minimal infiltration. Preoperative and postoperative TA regimen (paclitaxel 270 mg, epirubicin Star 110mg) chemotherapy 4 times (1/3 weeks), no complex