曾报道经前期综合征女性在黄体期时其血清黄体酮代谢物别孕烯醇酮低于无症状者。多年来将本征原因归咎于在黄体期时有卵巢激素分泌异常,尤为黄体酮不足,因此用黄体酮栓剂治疗。但深入研究不能证实黄体酮缺少,黄体酮栓剂治疗无效。近来发现用雌二醇及黄体酮可使本征患者出现典型 It has been reported premenstrual syndrome women in the luteal phase when the serum progesterone metabolites Pregnenolone less than asymptomatic. Over the years attributed the intrinsic causes of ovarian hormone secretion in the luteal phase is abnormal, especially lack of progesterone, so suppository treatment with progesterone. However, in-depth study can not confirm the lack of progesterone, progesterone suppository therapy ineffective. Recently found that with estradiol and progesterone can make the typical patients appear typical