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胸、腹腔积液细胞学涂片的诊断准确率据称有时可达94.0％。但因积液是一种很好的培养基,细胞在内可以繁殖及退化。不论良性或恶性细胞在形态上的变化都很大,不易认识,鉴别常有困难。为此我们尝试建立一种新的恶性肿瘤的辅助诊断方法,对54例72次胸、腹腔积液细胞进行了染色体分析,并与脱落细胞涂片检查、病理诊断和临床随诊结果相对照,以探讨染色体分析在某些恶性肿瘤的诊断价值;在39例临床确诊为恶性肿瘤的患者中,35例的积液细胞标本中发现相当数量的有丝分裂相,染色体数目呈明显的多倍性和非整倍性,并含有各种类型的畸变,一些病例发现为特异的标记染色体;另4例未发现足够的分裂相。15例原
Diagnostic accuracy of thoracic and ascitic cytology smears is sometimes claimed to sometimes reach 94.0%. However, because fluid is a good medium, the cells can reproduce and degenerate. Regardless of the morphological changes of benign or malignant cells are large, difficult to recognize, identification often difficult. To this end, we try to establish a new method for the diagnosis of malignant tumors. Chromosome analysis was performed in 54 cases of 72 cases of pleural and peritoneal effusion cells. Compared with the results of exfoliated cell smears, pathological diagnosis and clinical follow-up, To investigate the diagnostic value of chromosome analysis in some malignant tumors; in 39 cases of clinically diagnosed patients with malignant tumors, 35 cases of fluid cell samples found a significant number of mitotic phase, the number of chromosomes was significantly polyploidy and non- Euploidy, and contains various types of distortion, some cases found to be specific marker chromosome; the other 4 cases did not find enough split phase. 15 cases of the original