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目的探讨无创性超声对感染致婴儿肝炎综合征(婴肝征)疾病诊断及治疗效果、疾病转归的临床应用价值。方法选取感染致婴肝征患儿,分别于急性期、恢复期及临床治愈期探测肝静脉、肝动脉及门静脉的内径(DPV)、门静脉最大血流速(PVVmax;肝动脉收缩期最大血流速(PSV)、舒张期最大血流速(EDV)及阻力指数(RI)、肝静脉频谱波形(HVSW)特点。结果 (1)病例组比对照组肝脏轻度肿大、DPV增宽、PVVmax增快、PHAPSV增快,PHA RI增高、DHV减小。2组比较差异有统计学意义(P<0.01)。(2)PHAEDV、DPHA 2组比较差异无统计学意义(P>0.05)。(3)病例组HVS以HV1型为主,对照组以HV0型为主。(4)相关分析表明,PHAPSV和PHARI及HVSW与感染致婴肝征病情程度呈较好正相关(r=0.87和0.78,r=0.55,P<0.01)。结论肝脏超声血流动力学及频谱波形较客观地反映了感染致婴肝征的病情,为临床提供更多的信息,具有临床应用价值,有望成为感染致婴肝征诊断、治疗效果评价及预后判断的一种无创、有效的方法。
Objective To investigate the clinical value of noninvasive ultrasound in the diagnosis, treatment and prognosis of infant hepatitis syndrome. Methods Infants with infantile liver disease were selected to detect the diameter of the hepatic vein, hepatic artery and portal vein (DPV), the maximum blood flow velocity of the portal vein (PVVmax; the peak systolic blood flow of the hepatic artery) during acute phase, convalescence phase and clinical cure. PSV, EDV, RI and HVSW.Results (1) Compared with control group, liver enlargement, DPV broadening, PVVmax (P <0.01). (2) There was no significant difference between PHAEDV and DPHA 2 groups (P> 0.05). (P> 0.05) 3) HVS was predominant in HVS and HV0 in control group. (4) Correlation analysis showed that PHAPSV, PHARI and HVSW had positive correlation with the severity of infection (r = 0.87 and 0.78 , r = 0.55, P <0.01) .Conclusion The liver ultrasound hemodynamics and spectral waveform objectively reflect the condition of infantile liver infection, provide more information for clinical application, have clinical value and are expected to become infected A noninvasive and effective method for the diagnosis of infantile liver syndrome, evaluation of therapeutic effect and prognosis.