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目的观察静脉应用胺碘酮治疗治疗快速心律失常的临床疗效和安全性。方法112例快速心律失常患者,首剂静注负荷量胺碘酮150mg10分钟注入,继之以1.0mg/min微量泵持续泵入6h,以后0.5mg/min维持,最长维持48h后改为口服,若心律控制不满意,可间隔15min～30min后再给150mg的追加负荷量,24h总剂量在2000mg以内。结果有效率85.7%,副反应4.5%。结论静脉应用胺碘酮治疗快速心律失常安全且有效。
Objective To observe the clinical efficacy and safety of intravenous amiodarone in the treatment of tachyarrhythmia. Methods One hundred and twelve patients with tachyarrhythmia were injected with the first dose of amiodarone 150mg for 10 minutes, followed by continuous infusion of 1.0mg / min micro pump for 6h, and then 0.5mg / min for maintenance. The longest dose of amiodarone was maintained for 48h and then orally , If the heart rate control is not satisfied, can be separated 15min ~ 30min and then to 150mg additional load, 24h total dose within 2000mg. The results were 85.7% efficient, side effects 4.5%. Conclusion Intravenous amiodarone is safe and effective in the treatment of tachyarrhythmias.