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目的探讨注射用炎琥宁联合酚妥拉明治疗婴幼儿毛细支气管炎的临床疗效。方法选取2013年1月—2015年3月钦州市第一人民医院收治的毛细支气管炎患儿98例,随机分为观察组与对照组,各49例。对照组患儿予以利巴韦林治疗,观察组患儿予以注射用炎琥宁联合酚妥拉明治疗。观察两组患儿临床疗效、临床症状改善时间(体温恢复时间、肺部啰音消失时间、咳嗽消失时间)、住院时间及不良反应发生情况。结果观察组患儿总有效率高于对照组,差异有统计学意义(P<0.05);观察组患儿体温恢复时间、咳嗽消失时间、肺部啰音消失时间、住院时间短于对照组,差异有统计学意义(P<0.05);两组患儿均未发生严重不良反应。结论注射用炎琥宁联合酚妥拉明治疗婴幼儿毛细支气管炎的临床疗效显著,可改善患儿临床症状,减轻患儿痛苦,缩短住院时间,且不良反应小。
Objective To investigate the clinical efficacy of injection of mesylate combined with phentolamine in the treatment of infantile bronchiolitis. Methods From January 2013 to March 2015, 98 children with bronchiolitis admitted to First People’s Hospital of Qinzhou were randomly divided into observation group and control group, with 49 cases in each group. The control group was treated with ribavirin, and the observation group was treated with injection of Yan Hu Ning and phentolamine. The clinical curative effect, clinical symptom improvement time (body temperature recovery time, pulmonary rales disappearance time, cough disappear time), hospitalization time and adverse reactions were observed in two groups. Results The total effective rate in observation group was higher than that in control group (P <0.05). The recovery time, cough disappearance time, disappearance of pulmonary rales and hospital stay in observation group were shorter than those in control group The difference was statistically significant (P <0.05); two groups of children did not occur serious adverse reactions. Conclusion Injection of mesylate combined with phentolamine treatment of infantile bronchiolitis significant clinical effect, can improve the clinical symptoms of children, reduce pain in children, shorten the hospital stay, and adverse reactions.