为评价新生儿乙型肝炎疫苗接种后的效果，对济钢新村８８２ 名在新生儿期接种乙肝疫苗者进行了调查，检查其五项指标（ Ｈ Ｂｓ Ａｇ ，抗— Ｈ Ｂｓ ， Ｈ Ｂｅ Ａｇ ，抗— Ｈ Ｂｅ 和抗— Ｈ Ｂｃ） 。发现 Ｈ Ｂｓ Ａｇ 阳性率明显降低，为０２３ ％ ，抗— Ｈ Ｂｓ 阳性率升高，为４０９３ ％ ，但比现场实验低，不同医院接种者抗— Ｈ Ｂｓ 阳性率不同。结果说明乙肝疫苗效果明显，但实际接种中可能出现问题，包括储存等，需引起基层工作者的注意。 To evaluate the effect of hepatitis B vaccination in newborns, 882 HBsAg vaccinated in neonatal period were investigated in Hsinchuang Village to examine the five indicators (H Bs Ag, anti-H Bs, H Be Ag, Anti-H Be and anti-H Bc). It was found that the positive rate of Hbs Ag was significantly reduced (023%) and the positive rate of anti - H Bs was 4093%. However, the positive rate of anti - H Bs in different hospital vaccines was lower than that in field test. The results show that hepatitis B vaccine has obvious effect, but problems may occur in actual vaccination, including storage, which needs to attract the attention of grassroots workers.