论文部分内容阅读
采用抗肌动蛋白单克隆抗体HHF35和抗细胞角蛋白单克隆抗体AE1/AE3对10例良性淋巴上皮病变和3例恶性淋巴上皮病变中上皮性成分的构成细胞进行了免疫组织化学研究。结果发现：良性淋巴上皮病变中上皮岛构成细胞在部分HHF35呈阴性，仅在外周可见少许HHF35阳性细胞。AE1／AE3抗体在上皮岛构成细胞中大部分呈阳性。恶性淋巴上皮病变中癌巢内AE1／AE3抗体呈弥漫阳性，HHF35抗体主要分布在癌巢外周细胞。讨论了良性淋巴上皮的发生、发展、诊断及鉴别诊断方面存在的问题。
Immunohistochemistry was performed on the constitutive cells of epithelial components in 10 cases of benign lymphoepithelial lesions and 3 cases of malignant lymphoepithelial lesions by anti-actin monoclonal antibody HHF35 and anti-cytokeratin monoclonal antibody AE1 / AE3. The results showed that epithelial island cells in benign lymphoepithelial lesions were negative in some HHF35, and only a few HHF35 positive cells were seen in the periphery. The AE1 / AE3 antibodies are mostly positive in epithelial island-forming cells. AE1 / AE3 antibodies in neoplastic neoplasms of malignant lymphoepithelial lesions were diffusely positive, while HHF35 antibodies were mainly located in peripheral neoplasms of cancer nests. The problems of the occurrence, development, diagnosis and differential diagnosis of benign lymphoid epithelium were discussed.