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目的探讨老年高血压病患者血压昼夜节律变化与超敏C反应蛋白、颈动脉斑块的关系。方法将95例老年原发性高血压病患者按照24h动态血压检测结果分为A、B两组:A组为杓形组,共30例;B组为非杓形组,共65例,分别检测血清超敏C反应蛋白水平、超声测定颈动脉粥样硬化斑块程度。结果B组的超敏C反应蛋白水平明显高于A组(P<0.01),B组的颈动脉斑块分级明显高于A组(P<0.01)。结论老年高血压病患者血压昼夜节律变化与炎症反应、颈动脉粥样硬化关系密切。
Objective To investigate the relationship between circadian rhythm of blood pressure and hypersensitive C-reactive protein and carotid plaque in elderly patients with essential hypertension. Methods Ninety-five elderly patients with essential hypertension were divided into two groups according to 24h ambulatory blood pressure test: group A was pacifier-shaped group, a total of 30 cases; group B was non-pacifier-shaped group, a total of 65 cases, respectively Serum high-sensitivity C-reactive protein levels were measured and the degree of carotid atherosclerotic plaque was measured by ultrasound. Results The level of hypersensitive C-reactive protein in group B was significantly higher than that in group A (P <0.01). The carotid plaque grade in group B was significantly higher than that in group A (P <0.01). Conclusion The changes of circadian rhythm of blood pressure in elderly patients with hypertension are closely related to inflammatory reaction and carotid atherosclerosis.