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为评价新生儿缺氧缺血性脑病（ＨＩＥ）预后，对５３例ＨＩＥ患儿进行观察，其中３０例进行ＣＴ分度，５３例生后第３天测血清神经元特异性烯醇酶（ＮＳＥ）浓度，５０例（３例死亡）在生后３个月、６个月时用Ｇｅｓｅｌ法检测其神经发良情况。结果显示ＣＴ分度和血清ＮＳＥ检测法预测预后的敏感性分别为１００％和８５％；特异性分别为４５％和９０９１％。提示血清ＮＳＥ检测预后价值优于ＣＴ分度。
To evaluate the prognosis of neonates with hypoxic-ischemic encephalopathy (HIE), 53 HIE infants were observed. Thirty patients underwent CT grading. On the third postnatal day 53, serum neuron-specific enolase (NSE ) Concentration, 50 cases (3 deaths) were detected by Gesel method at 3 months and 6 months after birth. The results showed that the sensitivity of CT classification and serum NSE detection prognosis were 100% and 85% respectively; the specificity was 45% and 9091% respectively. Prompted serum NSE detection prognostic value is better than CT classification.