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[目的]研究益气养阴润肠方对小鼠肠道动力的影响。[方法]小鼠40只,随机分为益气养阴润肠方高剂量(47.84g·kg-1·d-1)组、中剂量(23.92g·kg-1·d-1)组、低剂量(11.96g·kg-1·d-1)组、正常组、新斯的明组(阳性组)。实验7d后处死所有小鼠,测碳末推进率。[结果]阳性组、益气养阴润肠方各剂量组的碳末推进率均明显提高,与正常组比较,差异有统计学意义(P<0.0 1)。[结论]中医益气养阴润肠法汤剂对小鼠肠道动力有明显的促进作用。
[Objective] To study the effect of Yiqi Yangyin Runchang Formula on intestinal motility in mice. [Method] Forty mice were randomly divided into high dose (47.84g · kg-1 · d-1) group and middle dose (23.92g · kg-1 · d-1) Low dose (11.96g · kg-1 · d-1) group, normal group, neostigmine group (positive group). All mice were sacrificed 7 days after the experiment to determine the carbon advancing rate. [Results] The carbon advancing rate in each group of positive group and Yiqi Yangyin Runchang group were significantly increased, compared with the normal group (P <0.01). [Conclusion] The traditional Chinese medicine “Yiqi Yangyin Runchang Decoction” can obviously promote intestinal motility in mice.