酰胺质子转移成像在脑肿瘤中的研究进展

来源 :国际医学放射学杂志 | 被引量 : 0次 | 上传用户：wwzly

【摘要】

：

酰胺质子转移(APT)成像是一种基于化学交换饱和转移(CEST)的分子MRI技术.APT成像在胶质瘤术前分级、基因突变的预测、脑肿瘤的鉴别及治疗后评估等方面显示了良好的应用前景.

【作者】

：

刘怀贵李威

【机构】

：

天津医科大学总医院医学影像科,天津,300052

【出处】

：

国际医学放射学杂志

【发表日期】

：

2020年1期

【关键词】

：

酰胺质子转移化学交换饱和转移蛋白质磁共振成像脑肿瘤

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论文部分内容阅读

酰胺质子转移(APT)成像是一种基于化学交换饱和转移(CEST)的分子MRI技术.APT成像在胶质瘤术前分级、基因突变的预测、脑肿瘤的鉴别及治疗后评估等方面显示了良好的应用前景.但一些病理改变(如富含蛋白的囊肿、血肿、脑转移瘤的周围水肿区)也可表现为APT信号增加,要注意与恶性肿瘤的鉴别.综述CEST/APT成像的原理、临床应用、局限性及发展方向.

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