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研究了萎缩性胃炎 (CAG)与海拔、气压、和季节之间的关系 ,从气象角度探讨CAG的发病机制。结果提示 :气压与CAG呈负相关 ,低气压是高原地区CAG发生的重要因素 ,气压变化是形成季节高峰的原因。低气压通过三个环节诱发CAG :一是使胃蠕动减慢 ,排空时间延长 ;二是低氧分压促使红细胞代偿性增多 ,血液粘稠度增加 ;三是低气压使胃腔气体扩张 ,对胃壁血管的压力增大。导致攻击因子增强 ,胃粘膜防御功能降低 ;胃粘膜易于受损产生炎症 ,浅表病变不易痊愈 ,最终发展成CAG。
The relationship between atrophic gastritis (CAG) and altitude, air pressure, and seasons was studied, and the pathogenesis of CAG was discussed from the meteorological point of view. The results suggest that there is a negative correlation between barometric pressure and CAG. Low baroclinic pressure is an important factor for the occurrence of CAG in plateau area. The change of barometric pressure is the reason for the formation of seasonal peak. Low pressure induced by three aspects of CAG: First, slowing the gastric motility, emptying time; Second, hypoxia partial pressure to promote compensatory increase of red blood cells, increased blood viscosity; Third, low pressure to gas expansion of the stomach cavity , The pressure on the stomach wall blood vessels increased. Resulting in enhanced attack factor, decreased gastric mucosal defense; gastric mucosa prone to inflammation, superficial lesions difficult to heal, eventually developing into CAG.