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正常女性在50岁左右,出现以月经紊乱为主要表现的临床症候群,预示着绝经期的开始,这是妇女一生中又一个重要的生理、心理改变与适应时期。以生殖内分泌改变为主的一系列解剖与生理变化。常是此期一些常见病的原因。 1 卵巢的变化一般认为始基卵泡或卵母细胞的耗尽是绝经的主要原因。有研究证明,6～9岁的女孩平均有484000个始基卵泡。性成熟后,每个月经周期均有一批卵泡不同程度地发育,成熟卵泡排卵后,其余卵泡闭锁。40～44岁时,只剩下8000个左右卵泡。绝经期不仅始基卵泡所剩不多,而且残余卵泡对促性腺激素的敏感性降低,排卵次数日益减少。即使有排卵,也常由于卵泡发育不良,造成黄体发育不全或黄体功能早衰,
Normal women at the age of 50, there are menstrual disorders as the main manifestation of clinical syndrome, indicating the beginning of menopause, which is another woman’s life and an important physiological and psychological changes and adapt to the period. A series of anatomical and physiological changes dominated by reproductive endocrine changes. Often some of the common causes of this period. A change in the ovary It is generally believed that the depletion of primordial follicles or oocytes is the main cause of menopause. Studies have shown that 6 to 9-year-old girl on average 484,000 primordial follicles. After sexual maturity, each batch of menstrual cycle has a number of follicles to varying degrees of development, mature follicles after ovulation, the other follicles atresia. 40 to 44 years old, leaving only about 8,000 follicles. Not only is there not much primordial follicles left in menopause, and the residual follicles are less sensitive to gonadotrophin and the number of ovulation is decreasing day by day. Even ovulation, often due to follicular dysplasia, resulting in corpus luteum hypoplasia or premature ejaculation,