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目的探讨不同振动阈值(VPT)危险分度的T2DM患者临床特点。方法采用Bio-thesiometer感觉定量检查仪测定T2DM患者下肢的VPT。根据VPT的结果将患者分为低度风险组(0～15V)、中度风险组(16～25V)和重度风险组(>25V),并探讨不同VPT风险组的临床特点和构成比,以及不同VPT危险分度和病程的关系。结果 VPT中、重度风险组的年龄、HbA1c和病程高于低度风险组(P<0.05);VPT中度受损占26.2%,重度受损占9.2%;中、重度风险组存在明显血脂代谢紊乱;胰岛β细胞功能指数(HOMA-β)中重度风险组明显低于低风险组(P<0.05和P<0.01)。结论 T2DM患者VPT受损与年龄、病程、HbA1c、HOMA-β和血脂密切相关。
Objective To investigate the clinical features of T2DM patients with different risk threshold (VPT) risk classification. Methods The VPT of lower extremities in T2DM patients was measured by Bio-thesiometer sensory quantitative test. According to the results of VPT, patients were divided into low risk group (0-15V), moderate risk group (16-25V) and severe risk group (> 25V), and to explore the clinical features and constitutional ratios of different VPT risk groups Relationship between different VPT risk classification and course of disease. Results The age, HbA1c and duration of VPT were higher than those of low-risk group (P <0.05). VPT moderate damage was 26.2% and severe damage was 9.2%. In moderate and severe risk group, there was significant blood lipid metabolism (HOMA-β) moderate-severe risk group was significantly lower than the low-risk group (P <0.05 and P <0.01). Conclusions The impairment of VPT in T2DM patients is closely related to age, course of disease, HbA1c, HOMA-β and lipids.