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目的:分析胃肠道炎性纤维性息肉(IFP)的临床诊断方法。方法:选取2009年1月到2011年1月间我院收治疗的60例IFP患者,回顾性分析其临床资料,研究其病理学及免疫组织学特征。结果:患者的临床表现以纤维血管增生和胃肠道粘膜下出现息肉样肿块为主,组织学特征为嗜酸性粒细胞浸润与特征性排列,免疫组化检测发现病变组织表达为肌纤维与纤维母细胞标记。患者的治疗方法为内镜下摘除或手术切除,出院后接受为期1~5年的随访,疾病复发者6例,经手术切除后控制病情,患者均恢复良好,无1例死亡。结论:作为一种少见的肠道良性病变,IFP的发病原因尚不明确,可能是对损伤、异物、感染等产生应激反应,导致发病,病理组织学改变较为典型,但需要和其他息肉样病变或胃肠道肿瘤作鉴别诊断,病理学检查与免疫组织学检查的诊断准确率高。
Objective: To analyze the clinical diagnosis of gastrointestinal inflammatory fibrillary polyps (IFP). Methods: Sixty IFP patients admitted to our hospital from January 2009 to January 2011 were retrospectively analyzed for their clinical data and pathological and immunohistological features. Results: The clinical manifestations of patients with fibrovascular hyperplasia and gastrointestinal submucosal polypoid tumor-like, histological features of eosinophil infiltration and characteristic arrangement, immunohistochemistry found that the lesion was expressed as muscle fibers and fibroids Cell markers. Patients treated by endoscopic removal or surgical resection, discharged after a period of 1 to 5 years of follow-up, 6 cases of disease recurrence after surgical excision to control the disease, the patients recovered well, no one died. Conclusion: As a rare benign intestinal pathology, the cause of IFP is not yet clear, which may be due to stress, such as injury, foreign body and infection, leading to the onset of pathological changes. However, it is necessary to compare with other polyps Lesions or gastrointestinal tumors for differential diagnosis, pathological examination and immunohistological diagnosis of high diagnostic accuracy.