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目的探讨综合疗法治疗井下煤矿工人功能性消化不良临床效果。方法 89例功能消化不良煤矿井下工人,随机分为对照组(42例)和观察组(47例)。两组均给予常规药物治疗,观察组同时给予心理干预和氟哌噻吨美利曲辛片综合治疗,比较两组治疗效果及不良反应。结果治疗8周后,观察组患者总有效率为91.49%,对照组为71.43%,两组总有效率比较差异有统计学意义(χ2=7.49,P<0.05)。观察组患者中发生不良反应5例,其中睡眠异常2例,头晕1例,便秘2例,不良反应发生率为10.64%,对照组患者中发生不良反应4例,其中睡眠异常l例,头晕2例,便秘1例,不良反应发生率为9.52%。两组患者不良反应发生率比较差异无统计学意义(P>0.05)。结论井下煤矿工人患功能性消化根据患者实际情况,进行综合疗法治疗能取得良好疗效,且无严重不良反应,可用于临床。
Objective To investigate the clinical effect of comprehensive therapy in treating functional dyspepsia in underground coal miners. Methods 89 cases of dyspepsia coal mine workers were randomly divided into control group (42 cases) and observation group (47 cases). Both groups were given conventional drug treatment, the observation group were given psychological intervention and flupentixol MTX tablets comprehensive treatment, the treatment effect and adverse reactions were compared between the two groups. Results After 8 weeks of treatment, the total effective rate was 91.49% in the observation group and 71.43% in the control group. There was significant difference between the two groups in total effective rate (χ2 = 7.49, P <0.05). There were 5 cases of adverse reactions in the observation group, including 2 cases of sleep abnormality, 1 case of dizziness and 2 cases of constipation. The incidence of adverse reactions was 10.64%. There were 4 cases of adverse reactions in the control group, including 1 cases of sleep abnormalities and 2 cases of dizziness Cases, constipation in 1 case, the incidence of adverse reactions was 9.52%. There was no significant difference in the incidence of adverse reactions between the two groups (P> 0.05). Conclusion Downhole coal miners suffering from functional digestion according to the actual situation of patients, comprehensive treatment can achieve good results, and no serious adverse reactions, can be used in clinical.