目的 :建立紫苏子有效成分α -亚麻酸的气相色谱测定法。方法 :色谱条件为 15 %丁二酸二乙二醇聚酯(DEGS)色谱柱 ,柱温 182℃ ,FID检测器 ,内标为十七碳酸乙酯。结果 :α -亚麻酸乙酯浓度在 0 42 92～ 2 146 0mg·mL-1范围内呈线性关系 (r=0 9999) ,加样平均回收率为 10 2 8% (RSD =0 73% )。结论 :该法简便 ,灵敏 ,易操作 ,为紫苏子生药质量评价提供了一个新的实用方法 Objective : To establish a gas chromatographic method for the determination of α-linolenic acid, the active ingredient of Perilla frutescens. Methods: The chromatographic conditions were 15% DEGS chromatography with a column temperature of 182°C, FID detector and internal standard of ethyl ester of 17-carbonate. Results: The concentration of α-linolenic acid was linear in the range of 0 42 92 to 2 146 0 mg·mL -1 (r=0 9999). The average recovery rate was 102 8% (RSD =0 73%). . Conclusion : This method is simple, sensitive, and easy to operate. It provides a new practical method for the quality evaluation of Perilla