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目的探讨慢性鼻窦炎功能性鼻内镜患者术后口服氨溴索区别于氨溴索冲洗鼻腔的疗效及应用价值。方法将192例鼻窦炎患者随机分为4组,治疗一组48例采用术后口服氨溴索治疗,治疗二组48例采用氨溴索行鼻内镜术后鼻腔冲洗,治疗三组48例患者采用联合治疗方法,对照组48例无特殊治疗方案。随访6个月,观察比较四组疗效及术后术腔上皮化时间。结果治疗组疗效均优于对照组。联合治疗三组疗效均优于单一治疗组(P<0.05)。结论功能性鼻内镜患者术后口服氨溴索及氨溴索鼻腔冲洗联合治疗具有减轻术腔水肿、缩短术腔上皮化时间,促进术腔愈合及无副作用的优点。
Objective To investigate the efficacy and clinical value of oral ambroxol in patients with chronic sinusitis functional endoscopically different from ambroxol flush nasal cavity. Methods A total of 192 patients with sinusitis were randomly divided into 4 groups, one group treated 48 patients treated with ambroxol after treatment, the other 48 patients treated with ambroxol nasal endoscopy after nasal irrigation, the treatment of 48 cases in three groups Patients with combined treatment, control group 48 patients without special treatment. The patients were followed up for 6 months. The curative effect of the four groups and the postoperative period of epithelialization were observed and compared. Results The treatment group were better than the control group. The curative effect of the three groups were better than the single treatment group (P <0.05). Conclusions The combination of oral administration of ambroxol and ambroxol nasal irrigating after functional endoscopic surgery in patients with functional endoscopic surgery has the advantages of alleviating the edema of the cavity, shortening the time of epithelialization of the cavity, promoting the healing of the cavity and no side effects.