药物或毒物能由阴道粘膜吸收后进入血液,并在血液中保持一定的有效浓度,因之若由这一途径给药以达到避孕目的,当有其可取之处。尤其在Folkman等发现了装在聚硅胶管内的药物能通过该聚合物管壁缓慢地释放到周围的液体中去后,这一给药途径就更有实用意义。因为将装有避孕药物的硅胶管植入阴道时,其缓慢恒定的释放率 Drugs or poisons can be absorbed by the vaginal mucosa into the blood and maintain a certain effective concentration in the blood, so if it is administered by this route in order to achieve the purpose of contraception, it should have its merits. This route of administration is even more useful, especially after Folkman et al. Found that the drug contained in the silicone tube can be slowly released into the surrounding fluid through the polymer tube wall. Because silicone tubes containing contraceptives are implanted in the vagina, they have a slow, constant release rate