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三七Pnax notoginseng(Burk.)F.H.Ch-en特产云南和广西,医药上用于滋补强壮,止血化瘀,消肿止痛,治气血虚弱、跌打损伤、内出血等。最近发现具有治疗冠心病作用。为综合利用三七资源,我们将具有清凉解毒热作用的三七花用于治疗白内障及美尼尔氏综合症有效。三七花中含大量皂甙,有必要进行深入研究,以确定酸水解后所得各种皂甙元的结构。因此,我们进行了三七花皂甙元的研究。三七花总皂甙,经酸水解后,分离得5种皂甙元:三七花皂甙元A,B,C,D及E。皂甙B含量太少,未能确定结构。根据理化性质,~(13)C核磁共振谱及电子轰击质谱,确定三七花皂甙元A即是三七叶皂甙元A,系一种人参二醇的含氧庚环衍生物(1)。三七花皂甙元D(2)为达玛20(22)-烯3β,12β,25-三醇(dammar20(22)-en3β,12β25triol),即三七叶皂甙元C。三七花皂甙元E(3)为20(R)达玛烷3β,12β,20β,25-四醇(20(R)darmarr-ane-3β,12β,20,25tetrol),即三七叶皂甙元D。三七花皂甙元C与已知样品对照鉴定为人参二醇(Pa-
Notoginseng Pnax notoginseng (Burk.) F.H.Ch-en specialties Yunnan and Guangxi, medicine for nourishing strong, stop bleeding, reduce swelling and pain, cure blood weakness, bruises, internal bleeding and so on. It has recently been found to have a therapeutic effect on coronary heart disease. In order to make comprehensive use of Panax Resources, we will use Sanqi Flower, which has a cooling and detoxifying effect, for the treatment of cataract and Meniere’s syndrome. There is a lot of saponin in Panax notoginseng flowers, and it is necessary to conduct in-depth studies to determine the structures of various aglycone elements obtained after acid hydrolysis. Therefore, we conducted a study of Panax notoginseng. Panax notoginseng saponin, after acid hydrolysis, isolated five kinds of saponins: Panax notoginseng A, B, C, D and E. Saponin B content is too low to determine the structure. According to physicochemical properties, ~(13)C NMR spectroscopy and electron impact mass spectrometry, it was determined that Panaxa flower saponin A is saponins A, a panaxadiol derivative of oxygen (1). Notoginsenoside D(2) is Damma 20(22)-ene 3β,12β,25-triol (dammar20(22)-en3β, 12β25triol), ie, notoginsenoside C. The Radix notoginseng yuan E(3) is 20(R)dammarane 3β,12β,20β,25-tetraol (20(R)darmarr-ane-3β,12β,20,25tetrol), ie, notoginsenoside Yuan D. The Bacillus subtilis C was identified as known as Panaxadiol (Pa-