5-羟色胺作为一种重要的中枢神经递质或调质,是否参与生理性的血糖调节,目前还未见报道。本工作以2-脱氧葡萄糖作为一种应激性刺激,观察了在应激性血糖升高反应中,小鼠脑内5-羟色胺代谢与血糖水平的关系。结果表明,2-脱氧葡萄糖(100mg/kg,i.p.)可引起小鼠的血糖明显升高, Serotonin as an important central neurotransmitter or quenched and tempered, whether or not involved in physiological regulation of blood glucose, has not been reported. In this work, 2-deoxyglucose as a stress stimulus, observed in the response to stress-induced hyperglycemia, mouse brain serotonin metabolism and blood glucose levels. The results showed that 2-deoxyglucose (100mg / kg, i.p.) can cause mice significantly increased blood glucose,