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目的:分析糖尿病继发泌尿系感染的危险因素及发病特点。方法:选择糖尿病合并泌尿系感染299例,对性别、年龄、病程、空腹血糖、餐后2h血糖、糖耐量试验、糖化血红蛋白水平、尿流动力学及膀胱镜检查阳性等危险因素与发生泌尿系感染进行相关性分析,并分析尿培养病原菌检出情况。结果:相关分析结果显示,女性、年龄≥60岁、病程≥5年、空腹血糖水平≥10.0mmol/L、糖化血红蛋白水平≥8.0mmol/L、尿流动力学检查阳性与发生泌尿系感染显著或非常显著相关(P<0.05,P<0.01)。中段尿培养结果病原菌以革兰阴性菌为主,占65.2%,其中,居前两位的分别是大肠埃希菌、肺炎克雷伯菌。结论:糖尿病患者应正规治疗、控制血糖水平;发生泌尿系感染后及早应用敏感抗生素,防止病情迁延。
Objective: To analyze the risk factors and pathogenesis of urinary tract infection secondary to diabetes. Methods: A total of 299 patients with diabetes mellitus and urinary tract infection were selected. The risk factors such as gender, age, course of disease, fasting blood glucose, postprandial 2h blood glucose, glucose tolerance test, glycosylated hemoglobin, urodynamics, cystoscopy and other urinary tract infections Correlation analysis, and analysis of urine culture pathogen detection. Results: The results of correlation analysis showed that female, age≥60 years, duration of disease≥5 years, fasting blood glucose level≥10.0mmol / L, glycosylated hemoglobin level≥8.0mmol / L, urine flow test positive and urinary tract infection were significant or abnormal Significant correlation (P <0.05, P <0.01). The middle part of the results of urinary culture pathogenic bacteria to Gram-negative bacteria, accounting for 65.2%, of which the top two are Escherichia coli, Klebsiella pneumoniae. Conclusion: Patients with diabetes should be treated regularly to control blood sugar levels. Sensitive antibiotics should be used as soon as possible after urinary tract infection to prevent prolonged illness.