【摘 要】
：
Seneca Valley virus (SVV),a newly determined etiological agent of vesicular disease in swine,causes porcine idiopathic disease and occasional acute death in piglets.Recently,an increased number of SVV infection cases have been reported in the United State
【机 构】
：
State Key Laboratory of Veterinary Etiological Biology,National Foot and Mouth Diseases Reference La
论文部分内容阅读
Seneca Valley virus (SVV),a newly determined etiological agent of vesicular disease in swine,causes porcine idiopathic disease and occasional acute death in piglets.Recently,an increased number of SVV infection cases have been reported in the United States (US) and China,resulting in significant economic losses to the swine industry.The first identification of SVV in China was reported in Guangdong Province,a major swine producing province.The cases of SVV were continuously reported in Guangdong in 2015 and 2016.However,the spread of SVV in Guangdong in 2017 remains unknown.In this study,we determined two new SVV strains,CH-GD-2017-1 and CH-GD-2017-2,from Guangdong.The genetic analysis suggested that the two Guangdong strains showed different characteristics to previous Guangdong strains.They showed lower nucleotide similarity with strains isolated in 2015 and 2016,and were more similar to the US strains.Phylogenetic analyses indicated that the new strains were clustered in a different clade with previous Guangdong strains.We found 28 mutated amino acids in the new strains,compared with the first Guangdong strain,SVV CH-01-2015.In the geographic analysis,we found that the US and China reported more SVV cases than other countries,and most of the SVV cases were reported in east and central China—of which,Guangdong Province is one of the major epidemic regions.In conclusion,our findings indicate that SVV continued to spread in Guangdong Province in 2017,and two different clades of SVVs have emerged in this region.
其他文献
Baculoviridae is a family of large DNA viruses that specifically infect insects.It contains four genera,Alpha-,Beta-,Gamma-,and Deltabaculovirus.Alphabaculovirus is further divided into Group Ⅰ and Ⅱ,and Group Ⅰ appears to be emerged most recently among a
China\'s AIDS epidemic started among people who inject drugs (PWID) in Ruili county-level city,a China-Myanmar border city of Yunnan Province,in 1989 (Fig.1).Since then HIV has spread rapidly across the country (He and Detels 2005).China launched a “Fou
Dear Editor,rnSince early December 2019, a large outbreak of pneumonia caused by a novel coronavirus (COVID-19) had emerged in Wuhan, China (Wu et al.2020a, b;Zhou et al.2020;Zhu et al.2020;Jiang and Shi 2020).Similar to severe acute respiratory syndrome
Dear Editor,rnTill January 20, 2020, the 2019-new coronavirus (2019-nCoV) has caused more than one hundred cases in Wuhan (WMHC 2020).During a retrospective study of recent pneumonia patients in our department, we found two patients who are likely being i
Nipah virus (NiV),a zoonotic paramyxovirus belonging to the genus Henipavirus,is classified as a Biosafety Level-4 pathogen based on its high pathogenicity in humans and the lack of available vaccines or therapeutics.Since its initial emergence in 1998 in
Dear Editor,rnIn December 2019, a novel human coronavirus caused an epidemic of severe pneumonia (Coronavirus Disease 2019,COVID-19) in Wuhan, Hubei, China (Wu et al.2020;Zhu et al.2020).So far, this virus has spread to all areas of China and even to othe
Primate bocaparvovirus (BOV) is a possible cause of respiratory disorders and gastroenteritis in humans.However,the diversity and evolution of these viruses remain largely unknown,despite the identification of a growing number of BOVs in non-human primate
Dear Editor,rnZika virus (ZIKV) is a mosquito-borne virus that belongs to the Flavivirus family along with dengue virus (DENV),yellow fever virus,West Nile virus,and Japanese encephalitis virus (Ming et al.2016).ZIKV is a singlestranded positive-sense RNA
Dear Editor,rnAn outbreak of unusual pneumonia in Wuhan, China recently was caused by infection of a novel type of coronavirus.The virus and disease were denoted as 2019-nCoV and COVID-19, respectively, by the World Health Organization (WHO).Most recently
Rasmussen\'s encephalitis (RE) is a rare pediatric neurological disorder,and the exact etiology is not clear.Viral infection may be involved in the pathogenesis of RE,but conflicting results have reported.In this study,we evaluated the expression of bot