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目的确定头孢羟氨苄分散片合理的处方及制备工艺,确保产品质量稳定。方法对处方和制备工艺进行筛选,通过相关试验考察工艺的稳定性。结果采用所选处方、工艺制备的头孢羟氨苄分散片外观光亮,硬度适中,溶出度好,分散性合格。结论按照所设计的处方及工艺制备的头孢羟氨苄分散片外观美观,质量稳定,其处方合理,工艺简单,适用于工业化生产。
Objective To determine the rational formulation and preparation of cefadroxil dispersible tablets to ensure the quality of the product is stable. Methods Prescription and preparation process were screened, and the stability of the process was investigated through relevant tests. Results The cefadroxil dispersible tablets prepared by the process showed bright appearance, moderate hardness, good dissolution and dispersibility. Conclusion The cefadroxil dispersible tablets prepared according to the prescriptions and processes designed by the authors have the advantages of good appearance, stable quality, reasonable prescription, simple process and suitable for industrialized production.