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[目的]利用1973—2013年黄浦区肿瘤登记数据,分析大肠癌的发病流行趋势,为卫生部门提供大肠癌的防治依据。[方法]从历年肿瘤登记数据中收集大肠癌发病资料,计算分性别和年龄别大肠癌发病率,采用1966年世界人口年龄结构进行标化。应用Join Point软件计算年度变化率(APC)。[结果]1973—2013年,黄浦区登记的大肠癌发病率为32.68/10万,标化发病率为20.78/10万;其中男性发病率为32.63/10万,标化发病率22.47/10万,女性发病率为32.73/10万,标化发病率19.52/10万。结肠癌发病率为19.18/10万,标化发病率12.06/10万,直肠癌发病率为13.50/10万,标化发病率8.72/10万;男、女性结肠癌和直肠癌的发病率均随着年龄的增长而上升。期间,大肠癌发病总体呈上升趋势,发病粗率的APC为9.90%,调整年龄结构之后上升有所减缓,APC为5.05%。[结论]上海市黄浦区大肠癌的发病率呈上升趋势,应加大防控力度。
[Objective] To analyze the epidemiological trend of colorectal cancer using the data of tumor registration from 1973 to 2013 in Huangpu District, and provide basis for the prevention and cure of colorectal cancer in the health department. [Methods] The incidence of colorectal cancer was collected from the data of tumor registration in the past years. The incidence of colorectal cancer by sex and age was calculated. The age structure of the world population in 1966 was used for standardization. Join Point software is used to calculate the annual rate of change (APC). [Results] The incidence of colorectal cancer registered in Huangpu District was 32.68 / 100 000 between 1973 and 2013, and the standardized incidence rate was 20.78 / 100 000. Incidence rate of male was 32.63 / 100 000, and the standardized incidence rate was 22.47 / 100 000 , Female incidence rate was 32.73 / 100000, the standardized incidence rate of 19.52 / 100000. The incidence of colon cancer was 19.18 / 100000, the standardization of incidence of 12.06 / 100000, the incidence of rectal cancer was 13.50 / 100000, the standardized incidence of 8.72 / 100000; male and female colon cancer and rectal cancer incidence were Rise with age. During this period, the overall incidence of colorectal cancer was on an upward trend. The incidence rate of APC was 9.90%. After adjusting for age structure, the increase was somewhat slowed down, with an APC of 5.05%. [Conclusion] The incidence of colorectal cancer in Huangpu District of Shanghai is on the rise. Prevention and control should be strengthened.