新疆高氟低碘环境与亚临床型克汀病

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本文对和田不同类型的碘缺乏病区,采用瑞文联合型中国农村智力常模表,分别随机抽样检查了7~14岁学生130名,并同步检查了听力、四项精神运动及甲状腺功能。高氟低碘病区儿童平均IQ71.09±6.84,平均听阈24.08±13.18dB,骨龄发育落后检出率28.5%,24小时甲状腺吸I~(131)”率59.87±14.63%,TSH 21.09±9.43μU/ml,亚克汀病患病率15.71%;低碘病区平均IQ 77.32±11.54,平均听阈19.91±7.23 dB,骨龄发育落后检出率13.5%,甲状腺吸I~(131)率50.26±19.25%,TSH 11.05±11.49μU/ml,亚克汀病患病率9.36%。补碘对照区平均IQ 95.76±17.52,平均听阈16.08±3.21 dB,骨龄发育落后检出率3.88%,甲状腺吸I~(131)率23.61±11.71%,TSH6.26±2.88μU/mL,亚克汀病患病率为3.20%。上述各项参数和病区之间,均有显著差异。说明在缺碘病区同时并存高氟摄入时,氟可加剧由缺碘而引起的中枢神经损害和体躯发育障碍。在104例精神轻度发育迟泄的儿童中,亚克汀病的检出率69.23%。 In this paper, different types of iodine deficiency wards in Hotan, using Rwenwen combined Chinese rural intelligence table, were randomly sampled 130 students aged 7 to 14, and simultaneous examination of the hearing, four psychomotor and thyroid function. The average IQ of children with high fluoride and iodine deficiency was IQ71.09 ± 6.84, the average hearing threshold was 24.08 ± 13.18dB, the detection rate of bone age was 28.5%, the rate of thyroid i ~ 131 in 24 hours was 59.87 ± 14.63% and TSH was 21.09 ± 9.43 μU / ml, and the prevalence of diachinine was 15.71%. The average IQ of low iodine disease was 77.32 ± 11.54, the average hearing threshold was 19.91 ± 7.23 dB, the detection rate of bone age was 13.5%, the rate of thyroid 131 Ⅰ was 50.26 ± 19.25%, TSH 11.05 ± 11.49μU / ml, and the prevalence rate of diachinine 9.36% .In iodine control area, the average IQ was 95.76 ± 17.52, the average hearing threshold was 16.08 ± 3.21 dB, the bone age was 3.88% ~ (131) rate of 23.61 ± 11.71%, TSH6.26 ± 2.88μU / mL, the prevalence of cretinism was 3.20% .All the above parameters and the ward were significantly different. In the coexistence of high fluoride intake, fluoride may exacerbate central nervous system impairment and somatic dysfunction caused by iodine deficiency.Among 104 children with mild mental retardation, the detection rate of diachinine was 69.23%.
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