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在人体血清中有一种与肿瘤相关的脱氧核糖核酸结合蛋白,分子量重64000,等电点5.9。采用萤光标记假单胞菌属芽胞的 DNA,以标定博莱霉素诱导的 DNA 片断的方法,测定病人血清中博莱霉素抑制蛋白(BIP)的含量。BIP 含量以特异性抑
There is a tumor-associated DNA binding protein in human serum, with a molecular weight of 64,000 and an isoelectric point of 5.9. The content of Bleomycin-inhibitory protein (BIP) in the patient’s serum was determined by labeling the DNA of Pseudomonas spores using a method of delineating bleomycin-induced DNA fragments. BIP content is specific