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[目的]探讨前哨淋巴结评估早期胃癌淋巴结转移的合理性,为早期胃癌微创化治疗提供基础。[方法]将单个转移淋巴结作为前哨淋巴结,回顾性分析26例单个淋巴结转移和191例无淋巴结转移早期胃癌病人的临床病理因素,并开展23例前哨淋巴结活检。[结果]Logistic回归分析显示浸润深度、肿瘤大小为影响早期胃癌前哨淋巴结转移的独立危险因素,前哨淋巴结的分布特点和早期胃癌淋巴结的转移特点基本一致;前哨淋巴结活检在早期胃癌中应用准确率为100%,敏感度为100%,特异性为100%。[结论]前哨淋巴结活检可准确反映早期胃癌的淋巴结转移状况,早期胃癌进行前哨淋巴结活检可避免淋巴结评估不足,以实现早期胃癌的微创化治疗。
[Objective] To investigate the rationality of sentinel lymph node in assessing lymph node metastasis of early gastric cancer, and to provide basis for minimally invasive treatment of early gastric cancer. [Methods] With single lymph node metastasis as the sentinel lymph node, 26 cases of single lymph node metastasis and 191 cases of early gastric cancer without lymph node metastasis were retrospectively analyzed, and 23 cases of sentinel lymph node biopsy were performed. [Results] Logistic regression analysis showed that the depth of invasion and tumor size were independent risk factors affecting sentinel lymph node metastasis of early gastric cancer. The distribution of sentinel lymph node was basically the same as that of lymph node metastasis of early gastric cancer. The accuracy of sentinel lymph node biopsy in early gastric cancer was 100%, sensitivity 100%, specificity 100%. [Conclusion] Sentinel lymph node biopsy can accurately reflect the status of lymph node metastasis in early stage gastric cancer. Sentinel lymph node biopsy in early stage gastric cancer can avoid the insufficient assessment of lymph node in order to realize minimally invasive treatment of early gastric cancer.