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目的评价Sysmex XE-2100分析仪幼稚粒细胞通道(IMI)在检测胸腹腔积液幼稚细胞的意义。方法对70例患者胸腹水应用IMI检测和病理细胞学检查进行幼稚细胞检测并分析。结果 24例肿瘤组的IMI检测阳性率为87.5%,高于病理细胞学检查的阳性率,有显著性差异(P=0.046);46例非肿瘤组的IMI检测阳性率为30.4%,高于病理细胞学检查的阳性率,但无显著性差异(P>0.05)。两种方法的一致性较好,K值为0.60(P=0.00)。结论 XE-2100 IMI在恶性胸腹水检测中与病理细胞学检查一性较好,敏感性高,简便、快捷,可用于临床胸腹腔积液标本中肿瘤细胞的常规筛查。
Objective To evaluate the significance of immature granulocyte-passageway (IMI) in the Sysmex XE-2100 analyzer for the detection of immature cells in ascites and pleural effusion. Methods Seventy patients with pleural and ascitic fluid were examined by IMI and pathological cytology for analysis of immature cells. Results The positive rate of IMI in 24 cases was 87.5%, which was significantly higher than that of pathological cytology (P = 0.046). The positive rate of IMI in 46 cases of non-neoplasm was 30.4% The positive rate of pathological cytology, but no significant difference (P> 0.05). Consistency between the two methods is better, with a K value of 0.60 (P = 0.00). Conclusion XE-2100 IMI has good cytotoxicity in malignant pleural effusion and ascites fluid examination. It is sensitive, simple and rapid and can be used for routine screening of tumor cells in pleural fluid and ascitic fluid.