溶组织内阿米巴和非致病的E.dispar关系密切,但在遗传学上又存在明显差异。虽然两者都寄生在人体肠道内,但难以从形态学上区分。溶组织内阿米巴能入侵组织,并引起出血性肠炎或肠外脓肿;而E.dispar为一种非致病寄生原虫。由于两者在遗传背景、细胞生物学及宿主方面高度相似,所以比较两者之间的差异能为分析、鉴别肠道内寄生原虫的致病因素提供一条途径。为此,作者用68种溶组织内阿米巴cDNA探针,对脉冲凝 Entamoeba histolytica and non-pathogenic E. Dispar close, but there are also significant differences in genetics. Although both are parasitic in the human gut, it is difficult to distinguish morphologically. Entamoeba histolytica can invade tissues and cause hemorrhagic colitis or extraintestinal abscess; and E. dispar is a non-pathogenic parasitic protozoan. As the two are highly similar in genetic background, cell biology and host, comparing the differences between the two can provide a way to analyze and identify the pathogenic factors of intestinal parasites. To this end, the authors used 68 E. histolytica cDNA probes for pulse coagulation