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作者回顾性研究了295例狼疮抗凝物(LA)阳性患者的临床、实验室及皮损的组织病理资料,着重讨论了LA与皮损的关系。295例中,70例有皮肤损害,其中女39,男31,平均年龄39岁(16～72岁),最常见的皮损是血栓性静脉炎综合征(34％),表现为水肿、红斑,伴有炎症性改变,多位于小腿后侧和踝部。其次为皮肤溃疡(30％),其边界锐利、疼痛,常多发、灶性,有中心或基底坏死,周围无炎症,愈后可留白色萎缩性瘢痕,多位于胫前和踝部。紫癜或淤斑占14％,其中2例有皮下血
The authors retrospectively reviewed histopathological data from 295 patients with positive lupus anticoagulant (LA) in clinical, laboratory, and lesional lesions, focusing on the relationship between LA and lesions. Of the 295 cases, 70 had skin lesions, 39 of them women and 31 with an average age of 39 years (16-72 years). The most common skin lesions were thrombophlebitis syndrome (34%) with edema, erythema , Accompanied by inflammatory changes, mostly in the back of the calf and ankle. Followed by skin ulcers (30%), the border sharp, painful, often multiple, focal, with central or basal necrosis, no inflammation around, after the more white atrophic scar may remain, mostly in the anterior tibial and ankle. Purpura or ecchymosis 14%, of which 2 cases of subcutaneous blood