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目的观察血塞通滴丸联合辛伐他汀与单独使用辛伐他汀治疗高脂血症的疗效。方法 160例高脂血症患者随机分为治疗组80例,给予血塞通滴丸每次50～100mg,3次/d,辛伐他汀片每晚20mg口服;对照组80例,单独应用辛伐他汀片每晚20mg口服,于用药前及用药4周测定总胆固醇(TC),甘油三酯(TG),高密度脂蛋白(HDL-C),低密度脂蛋白(LDL-C)。结果 TC由(6.8±1.05)mmol/L降至(4.92±0.48)mmol/L,TG由(3.54±0.62)mmol/L降至(1.75±0.55)mmol/L,HDL-C由(1.01±0.25)mmol/L升至(1.52±0.30)mmol/L,LDL-C由(3.95±0.41)mmol/L降至(2.93±0.52)mmol/L;对照组:TC由(6.79±0.59)mmol/L降至(5.95±0.47)mmol/L,TG由(3.51±0.49)mmol/L降至(2.95±0.48)mmol/L,HDL-C由(1.02±0.19)mmol/L升至(1.29±0.23)mmol/L,LDL-C由(4.01±0.35)mmol/L降至(3.75±0.44)mmol/L;二组比较结果差异有统计学意义(P<0.01)。结论血塞通滴丸联合辛伐他汀治疗高脂血症疗效优于单独应用辛伐他汀。
Objective To observe the therapeutic effect of Xuesaitong dripping pills combined with simvastatin and simvastatin alone on hyperlipidemia. Methods One hundred and sixty patients with hyperlipidemia were randomly divided into treatment group (n = 80), Xuesaitong dropping pills (n = 50 to 100mg, n = 3) and simvastatin tablets Total cholesterol (TC), triglyceride (TG), high density lipoprotein (HDL-C) and low density lipoprotein (LDL-C) were measured before treatment and 4 weeks after treatment. Results TC decreased from (6.8 ± 1.05) mmol / L to (4.92 ± 0.48) mmol / L, TG decreased from (3.54 ± 0.62) mmol / L to L to (1.52 ± 0.30) mmol / L and LDL-C from (3.95 ± 0.41) mmol / L to (2.93 ± 0.52) mmol / L in the control group; L decreased to (5.95 ± 0.47) mmol / L, TG decreased from (3.51 ± 0.49) mmol / L to (2.95 ± 0.48) mmol / L and increased from (1.02 ± 0.19) mmol / L to ± 0.23) mmol / L, and LDL-C decreased from (4.01 ± 0.35) mmol / L to (3.75 ± 0.44) mmol / L. There was significant difference between the two groups (P <0.01). Conclusion Xuesaitong drip pills combined with simvastatin treatment of hyperlipidemia is better than simvastatin alone.