吉林省1989~1996年口服脊髓灰质炎疫苗、麻疹疫苗效力及冷链运转效果评价

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对吉林省1989~1996年口服脊髓灰质炎(脊灰)疫苗(OPV)和麻疹疫苗(MV)经运输、贮存后的效价,以及冷链运转效果进行了评价。检测结果表明,1990~1996年共检测省卫生防疫站冷库OPV35批,达到出厂合格滴度(570logCCID50/人份)的25批,占7143%;1989~1996年,检测省卫生防疫站冷库MV49批,都达到合格滴度(35logCCID50/1ml)。从各级采样点检测的结果,与省卫生防疫站冷库相比较,无论是OPV还是MV,差异均无显著性(P>005)。由链头(省卫生防疫站冷库)至链尾(接种点),两种疫苗均保持较高的效价,提示我省自1989年以来冷链运转良好,而且MV稳定性较好,优于OPV。由于冷链的正常运转,使我省计划免疫工作质量有很大提高。OPV、MV的接种率、免疫成功率均达96%以上,发病率明显下降。 The effects of transport and storage of oral poliovirus (OPV) and measles vaccine (MV) in Jilin Province from 1989 to 1996 were evaluated, and the effect of cold chain operation was evaluated. The test results showed that during the period from 1990 to 1996, a total of 35 batches of OPV 35 batches, accounting for 71 43.4%, were obtained from the cold storage of the provincial health and anti-epidemic station cold storage, reaching the qualified titers (5  70logCCID50 / person), and from 1989 to 1996, Station cold storage MV49 batch, have reached qualified titers (3  5logCCID50 / 1ml). Results from all sampling points showed no significant difference (P> 005) between OPV and MV compared with that of provincial health and epidemic prevention stations. From the chain (provincial health and epidemic prevention station cold storage) to the end of the chain (point of vaccination), the two vaccines have maintained a high titer, suggesting that the province since 1989, the cold chain is running well, and the MV stability is better than OPV. Due to the normal operation of the cold chain, so that the quality of immunization programs in our province have greatly improved. The vaccination rate and immunization success rate of OPV and MV reached more than 96%, the incidence decreased significantly.
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