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目的总结胃肠肿瘤根治联合肝移植治疗晚期胃肠肿瘤并发肝脏多发转移的近期疗效。方法1例胃癌和2例直肠癌并发肝脏多发转移患者,分别接受胃癌和直肠癌根治、联合原位同种异体肝移植手术,其中1例因肺结核同时行左上肺部分切除术。结果3例患者无围手术期死亡。随访5-7个月,胃癌患者术后5个月死于肿瘤复发;1例直肠癌并肺结核患者术后7个月死于肝功能衰竭,无肿瘤复发;另1例直肠癌患者已完成3个月化疗,术后半年无复发,肝功能和血常规正常,精神食欲好,已恢复工作。结论胃肠肿瘤根治联合肝移植为部分晚期肿瘤患者提供了生存的希望,远期效果有待进一步观察。
Objective To summarize the short-term curative effect of radical combined with liver transplantation for the treatment of advanced gastrointestinal tumors with multiple liver metastases. Methods One case of gastric cancer and two cases of rectal cancer with multiple liver metastases were treated with radical resection of gastric cancer and rectal cancer combined with orthotopic liver transplantation. One case of pulmonary tuberculosis was treated by partial upper left lung resection. Results 3 patients without perioperative death. Followed up for 5-7 months, the gastric cancer patients died of tumor recurrence 5 months after surgery; 1 case of rectal cancer and pulmonary tuberculosis died of hepatic failure 7 months after operation without tumor recurrence; the other 1 case of rectal cancer patients completed 3 Month chemotherapy, no recurrence six months after surgery, liver function and blood normal, good appetite, has resumed work. Conclusions Radical gastrointestinal cancer combined with liver transplantation provides some hope of survival for some patients with advanced cancer. The long-term effect needs further observation.