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血纤维蛋白溶酶血中血纤维蛋白溶酶的主要作用是溶解新生栓塞.Back等的一项研究表明血纤维蛋白溶酶的血栓亲和力在纤维蛋白分解系统各组分中是最高的一个.自从Alkjaersig等发现被网着的纤维蛋白溶酶原被激活为血纤维蛋白溶酶,并在血栓中溶解纤维蛋白.对于其作用机理仍有争议.因此,人们怀疑外源的标记由纤维蛋白溶酶与血栓结合的量是否足以能得到外部显像结果.此外,血液中含有高浓度的血纤维蛋白溶酶抑制物,它会在血纤维蛋白溶酶刚注入体内就与其形成复合物,阻止其与血栓结合.一些临床试验报告了应用~(99m)Tc-血纤维
The main role of plasmin in plasmin in blood is to dissolve nascent embolism.A study by Back et al shows that the thrombus affinity of plasmin is the highest among the components of the fibrinolytic system Alkjaersig et al. Found that the net- work of plasminogen activates plasminogen and dissolves fibrin in the thrombus, and its mechanism of action remains controversial. Therefore, it is suspected that the exogenous label is composed of plasmin In addition, the blood contains a high concentration of plasmin inhibitors, which will form a complex with plasmin just after it is injected into the body to prevent it from reacting with Thrombosis. Some clinical trials report the use of ~ (99m) Tc-fibrils