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1975年2～3月,我科应用细胞色素 C 发生过敏2例,现报告如下。例1:王×,男,62岁,干部。因患慢性支气管炎、肺气肿、肺原性心脏病住院治疗。静脉注射50%葡萄糖液100毫升内加细胞色素 C 30毫克,注入20毫升时病人即感头面部、脚心发痒,四肢起风疹团块,眼发胀,球结膜充血。立即停止注射,肌肉注射非那根25毫克。40分钟后,症状消失,恢复正常。例2:刘×,男,48岁,干部。因患慢性支气管炎、风心病住院治疗。静脉注射50%葡萄糖液100毫升内加细胞色素 C 30毫克。约10分钟,病人感到头面部、脚心奇痒难耐,眼发胀,恶心呕吐,胸闷,心慌气短,头晕目眩,随即昏迷。面色苍白,球结膜充血,脉搏微弱,四肢发凉,血压测不到。
February 2 ~ March 1975, our department of cytochrome C allergy in 2 cases, are as follows. Example 1: Wang ×, male, 62 years old, cadres. Because of chronic bronchitis, emphysema, pulmonary heart disease hospitalized. Intravenous injection of 50% glucose solution 100 ml of cytochrome C 30 mg, injected 20 ml of the patient that head and face, itchy toes, limbs and rheumatoid clumps, eye swelling, conjunctival hyperemia. Immediately stop injection, intramuscular injection of phenanthrene 25 mg. After 40 minutes, the symptoms disappeared and returned to normal. Example 2: Liu ×, male, 48 years old, cadre. Due to chronic bronchitis, rheumatic disease hospitalized. Intravenous injection of 50% glucose solution 100 ml plus Cytochrome C 30 mg. About 10 minutes, the patient felt head and face, feet itch embarrassed, swelling eyes, nausea and vomiting, chest tightness, palpitation shortness of breath, dizzy, then unconscious. Pale, conjunctival hyperemia, weak pulse, cold limbs, blood pressure can not be measured.