论文部分内容阅读
病毒性肝炎病原学对甲型肝炎病毒(HAV)的研究表明,HAV是直径25~28毫微米的立体对称的微小病毒。至于它所含的核酸,到底是RNA或DNA,尚有待进一步的研究。在实验感染的猩猩、狨猴和甲型肝炎患者的粪便和血清中,以及猩猩的肝和胆汁中,皆可发现HAV。HAV可耐受60℃1小时的热力,但甲醛(0.25毫升/升)37℃作用72小时,或氯(1毫升/升)作用30分钟,都可使之灭活。乙型肝炎病毒(HBV)是一种直径42毫微米的双层球形颗粒(Dane颗粒),可分为核心与包膜两部分。乙型肝炎表面抗原(HBsAg)就是HBV的包膜,其分子量为3.7~4.6×10~6,
Viral hepatitis Etiology Studies on Hepatitis A virus (HAV) have shown that HAV is a sterically symmetrical parvovirus having a diameter of 25-28 nm. As for the nucleic acids it contains, RNA or DNA in the end, remains to be further studied. HAV can be found in the stool and serum of experimentally infected orangutan, marmoset and hepatitis A patients and in the livers and bile of orangutans. HAV can tolerate 1 hour of heat at 60 ° C, but formaldehyde (0.25 ml / l) for 72 hours at 37 ° C or chlorine (1 ml / l) for 30 minutes can inactivate HAV. Hepatitis B virus (HBV) is a double-layered spherical particle (Dane particle) with a diameter of 42 nm, which can be divided into two parts: core and envelope. Hepatitis B surface antigen (HBsAg) is the envelope of HBV, the molecular weight of 3.7 ~ 4.6 × 10 ~ 6,